Presentations

Abstract

Introduction:

Filler-induced alopecia is characterized by localized hair loss, often attributed to vascular compromise following dermal filler injections in particular facial regions. Though previously uncommon, the rising incidence of this complication underscores the importance of understanding and managing its intricacies.

Main Body:

We conducted a comprehensive literature review using PubMed. Our review included articles reporting filler-induced alopecia, summarizing the implicated filler types, areas of injection, pattern of hair loss, symptom onset, course progression, treatments, and overall prognosis. Among the documented cases of filler-induced alopecia, a majority involved the use of hyaluronic acid, while calcium hydroxylapatite and autologous fat were implicated in a smaller subset. Notably, no cases involving other dermal filler types were identified. Recovery times varied depending on the treatment interventions employed. Hyaluronidase (HAase) injections exhibited rapid restoration, with nearly normal hair density achieved within 3 to 4 months. Adjunctive therapies like minoxidil and platelet-rich plasma, in conjunction with HAase, notably facilitated hair regrowth. One case suggested the potential of recombinant bovine basic fibroblast growth factor gel, however, its efficacy was confounded by co- administration of minoxidil. Additionally, exploring alternative interventions like intralesional triamcinolone, warm compresses, and nitroglycerin are worth exploring due to the lack of robust clinical data supporting their efficacy in addressing this complication.

Conclusion:

Our study promotes awareness of filler-induced alopecia and its increasing incidence, while providing practical insights with evidence-based recommendations for effective management. We aim to equip dermatologists with current knowledge to proficiently manage this complication, thereby enhancing patient outcomes and safety standards in cosmetic procedures.