The Microscopy & Imaging Facility is equipped (1) upright and inverted fluorescence microscopes with digital cameras; (2) a Zeiss 510 Laser Scanning Confocal Microscope, with 3 lasers and a META system, which employs spectral signature analysis to separate up to 8 fluorochromes with highly overlapping emission spectra; (3) a JEOL 1200EXll transmission electron microscope with an AMT XR111 digital camera for ultrastructural examination of biological tissue. The Facility and EVMS have computers equipped with image analysis software (MetaMorph) and the director provides assistance and training in its use. An IVIS in vivo imager is also available through Comparative Medicine, with software analysis available in the Facility.