A clinical trial is a research study that is designed to test the effectiveness of new medical treatments or other medical interventions. Each study is designed to answer scientific questions and to find better ways to treat individuals with a specific disease.

All clinical trials conducted at EVMS are approved by the FDA and by the EVMS Institutional Review Board (IRB). EVMS Internal Medicine's clinical trials are listed by division below.

Strelitz Diabetes Center

Primary Investigator: Elias S. Siraj, MD

Summary: The purpose of this study is to evaluate the effects of dapagliflozin as compared with placebo on heart failure disease-specific biomarkers, symptoms, health status and quality of life in patients with chronic heart failure with preserved systolic function.

Point of contact: Henri Parson, PhD, or Norine Kuhn

Start date: 9/7/2017

You may be eligible to participate in this study if you:

  • Have been diagnosed with chronic heart failure
  • Are at least 18 years old

Primary Investigator: Aaron Vinik, MD, PhD, FCP, MACP, FACE

Summary: The primary objective of this study is to determine if oral Topiramate slows progression of Cryptogenic Sensory Peripheral Neuropathy (CSPN) in subjects with Metabolic Syndrome and pre-diabetes.

Point of contact: Carolina Casellini, MD, and Henri Parson, PhD

Start date: 03/27/2018

You may be eligible to participate in this study if you are:

  • Are at least 18 years old
  • Have signs of metabolic disease including abdominal obesity, pre-diabetes, high blood pressure and abnormal cholesterol/lipids
  • Have numbness and tingling on the feet

Primary Investigator: Elias S. Siraj, MD

Summary: The purpose of this study is to determine if semaglutide may reduce the risk of cardiovascular events (e.g, stroke, heart attack) in patients that are overweight or obese and have a history of cardiovascular disease.

Point of contact: Henri Parson, PhD, or Norine Kuhn

Start date: 12/1/2018

You may be eligible to participate in this study if you are:

  • Diagnosed with cardiovascular disease
  • Overweight or obese
  • At least 18 years old

Primary Investigator: Aaron Vinik, MD, PhD, FCP, MACP, FACE

Summary: This study is designed to better understand factors that impact or lead to the perception of fatigue in subjects diagnosed with either type 1 (T1DM) or type 2 diabetes mellitus (T2DM) who are who are between 18-80.

Point of contact: Carolina Casellini, MD and Henri Parson, PhD

Start date: 01/31/2017

You may be eligible to participate in this study if you are:

  • Are at least 18 years old
  • Have type 1 or type 2 diabetes